The College of Arts and Sciences is pleased to announce the continuation of the 利记sbo College of Arts and Sciences Seminar Series.
This lecture series invites the campus community to join us as we explore the relationships between the arts and sciences through a dedicated annual theme. Our three college departments -- Math and Computer Science; Humanities, Social Sciences, and Communication; and Natural Sciences -- invite internal and external speakers to help us discover links between each other's disciplines through seminars, lectures, and roundtable discussions.
Each event is free and open to the public. Pizza will be served at 12:15 prior to the event.
Experimental Curiosity
Through a diverse series of events hosted by our three departments, we invite the campus community to join us as we explore the relationship between experimentation and curiosity in the many senses of each term. How does experimentation fuel curiosity? How does curiosity lead to new experimental methods and approaches? How do researchers take their curiosity and transform it into tangible experiments that yield knowledge? How does experimentation and curiosity vary across disciplines? How does experimental curiosity change the way we approach our personal and professional development? Does it make us bolder in our quest to satisfy the unknown?
Upcoming Lecture
Thursday, October 17, 2024
12:30 p.m. - 1:30 p.m.
Location: S321
Speaker: Justin Dietrich, Principal Research Scientist II, AbbVie
Introduction to Small-Molecule Drug Discovery and the Application of Enabling Technology
Drug discovery requires collaboration across many core disciplines including chemistry, biology, biophysics, pharmacology, medicine, informatics, and engineering with the overarching goal to develop new therapies that can improve the lives of people who have conditions of unmet medical need. Justin Dietrich will introduce you to the small-molecule drug discovery process and walk you through the iterative cycle medicinal chemists constantly navigate to design optimized lead compounds, to synthesize them via organic chemistry, and to analyze their properties in assays representative of a desired biological response. The last section of Dietrich's talk will describe the application of DNA-Encoded Library screening. In this technology, large collections of individual small-molecules attached to DNA barcodes are screened against a biological target of interest and then decoded using next generation sequencing.
